Fracture risk before and after total hip replacement in patients with osteoarthritis: potential benefits of bisphosphonate use.
Prieto-Alhambra D., Javaid MK., Judge A., Maskell J., Kiran A., de Vries F., Cooper C., Arden NK.
The association between osteoarthritis (OA) and fractures remains unclear. OA patients have increased bone mass, but no corresponding decrease in fracture rate. This study was undertaken to determine the fracture rates in patients with hip OA undergoing a total hip replacement (THR), as compared with disease-free controls, and to assess the association between bisphosphonate use and postsurgery fracture risk.