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Since the advent of modern neuroimaging techniques, studies have been carried out to examine nociceptive processing within the human brain non-invasively. Combined with advances in immunohistochemistry, histology and genetics, we have been able to correlate more objective measures of nociceptive processing with the subjective experience that is pain. The result has produced a dramatic shift in our thinking about the neural circuitry involved in nociceptive processing, revealing that pain is much more than a submodality of the sense of touch.

Original publication

DOI

10.1016/j.conb.2005.06.010

Type

Journal article

Journal

Curr Opin Neurobiol

Publication Date

08/2005

Volume

15

Pages

478 - 487

Keywords

Afferent Pathways, Animals, Brain, Brain Mapping, Humans, Nociceptors, Pain